When attempting to steal a nuclear missile he was confronted by Batman and Aquaman. Chemo managed to infect Batman but Aquaman saved him. When Chemo attempted to steal the Nuke again. He was confronted by the Navy and Batman. Chemo eventually did get the nuke and it was revealed that Chemo had actually been working for the Brain. When destroying the Batboat, Batman ejected and went inside chemo. After he disabled the Nuke he threw three Bat Bombs and destroyed Chemo from the inside out. He later appears in the episode "Clash of the Metal Men" where he fights Batman by the docks and nearly beat him until the Metal Men came and defeated Chemo.